Under the wave of synthetic biology and green manufacturing, Guangdong Bien Biotechnology Co., LTD. (hereinafter referred to as "Bien Biotechnology") is becoming a game-breaker in the field of beauty raw materials with its independently developed biological fermentation technology. The company was established in 2019 and is located in the Guangqing Economic Special Cooperation Zone, Yingde City, Qingyuan City. It focuses on extracting highly active ingredients through microbial fermentation technology and provides natural, safe and efficient solutions for cosmetics and functional foods.

Technological Breakthrough: The Leap from the laboratory to mass production
The core technologies of Bien Bio focus on microbial fermentation and the extraction of active ingredients. Take Tremella fuciformis polysaccharides as an example. The company has increased the total sugar content of Tremella fuciformis polysaccharides to 39.05% by breeding high-yield strains and combining ultrafiltration membrane concentration and spray drying processes, far exceeding the 20.22% obtained by traditional plant extraction methods. This breakthrough not only enhances the moisturizing and soothing effects of polysaccharides, but also optimizes their skin feel, making them a star ingredient in high-end skin care product formulas. At present, this product has passed the full version of the safety assessment report and has been successfully applied to categories such as lotion and essence.

Another flagship product - BEN-063 Bien Women's Wine Lees, takes the whitening effect as its core competitiveness. Through tyrosinase inhibition experiments, it was verified that its whitening effect can replace chemical synthetic agents such as vitamin C ethyl ether, and the content of gamma-aminobutyric acid is four times that of similar products in Japan. It also has the functions of anti-wrinkle and firming. This raw material uses the filtrate of rice fermentation products as the base and is suitable for sensitive skin, meeting the current consumers' demand for "natural and non-irritating".

Innovation model: Deep integration of industry, academia and research
The R&D strength of Bien Biotech stems from its "industry-university-research-application" integrated model. The company has established a joint laboratory with Beijing University of Chemical Technology and Borui Xuan (Guangzhou) Research Co., LTD., focusing on topics such as strain selection and breeding, and optimization of fermentation processes. For instance, its patented technology "A Preparation Method of Filtrate and Lycytic Substances of Bifidobacterium bifidum Fermentation Products" (CN202410984482.2) significantly increases the content of lactic acid and acetic acid by regulating the fermentation conditions, endows the product with a stronger ability to regulate the skin microecology. In addition, the company has also collaborated with the China Trade Compliance Center to complete the safety assessment of raw materials and ensure their compliance upon entering the market, thereby shortening the cycle from research and development to the market.

Market layout: Cross-border extension from beauty products to food
The product matrix of Bien Biotech has covered two major fields: daily chemicals and food. In the field of daily chemicals, its bio-polysaccharides and probiotic raw materials have been applied by many international brands in anti-aging and repair products. In the food industry, the company's developed tremella fuciformis polysaccharides and plant fermentation products are used in functional beverages and dietary supplements. At the 2025 PCHi exhibition, the company announced that it would expand into the personal care sector, launching raw materials for shampoos and body washes based on fermentation technology to meet consumers' dual demands for scalp care and body cleansing.

Industry impact: Promoting green manufacturing and sustainable development
The bio-fermentation technology of Bien Bio not only enhances the performance of raw materials but also implements the ESG concept. Its fermentation process does not rely on forest resources. The strains complete their metabolism in closed tanks, reducing wastewater discharge by 80% and carbon emissions by 60%. The company has passed the GMPC and ISO22176 certifications. The production workshop is equipped with high-end testing instruments to ensure product safety and controllable quality.

In the future, as the market size of bio-fermentation is expected to exceed 314.7 billion yuan in 2029, Bien Bio plans to further expand its production capacity and join hands with upstream and downstream enterprises to build a raw material supply chain ecosystem. As General Manager Peng Tianzhi said, "The core of technology lies in solving practical problems, and our mission is to ensure that every drop of raw material carries the dual value of nature and science."